Clinical evidence

HealthGen's trajectory infrastructure is clinically validated through randomised controlled trials and real-world implementation studies across Singapore's healthcare system.

Randomised Controlled Trial

EMPOWER Trial

997 adults with type 2 diabetes in Singapore randomised to Empower+ app + wearable versus usual care.

Intervention group achieved significantly greater HbA1c reduction and improved patient activation scores.

3 months
0.80%
vs 0.49% control
12 months
1.15%
vs 0.67% control
HbA1c Reduction (%)
3 months
Intervention
0.80%
Control
0.49%
12 months
Intervention
1.15%
Control
0.67%
Intervention Components & Outcomes
Full intervention (n=201)
App • Wearable • CGM • Coaching
Higher response rateGreater HbA1c reduction
Digital-only (n=199)
App • Wearable
Meaningful improvement

Both arms showed improvement, with the full intervention achieving higher proportions of clinically significant HbA1c reduction

Comparative Effectiveness Trial

CARE Trial

400 adults with type 2 diabetes randomised to compare full intervention (app + wearable + CGM + coaching) versus digital-only (app + wearable).

Both arms improved HbA1c, but the full intervention arm showed larger within-arm reductions and a higher proportion achieving clinically significant improvement.

201 participants: Empower+ app, wearable, CGM, coaching
199 participants: Empower+ app and wearable only
Endpoints assessed at 12 and 24 weeks
Progress Report, May 2025

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